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Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
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Updated: Jun 6, 2026

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
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Hand pattern indicates prostate cancer risk.

A A Rahman1, A Lophatananon, S Stewart-Brown

  • 1Division of Epidemiology and Public Health, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK.

British Journal of Cancer
|December 2, 2010
PubMed
Summary
This summary is machine-generated.

The ratio of the index finger to ring finger length (2D:4D) may indicate prostate cancer risk. A higher 2D:4D ratio (longer index finger) is associated with a reduced risk of developing prostate cancer.

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Area of Science:

  • Andrology
  • Urology
  • Human Biology

Background:

  • Digit length ratios are established prenatally.
  • These ratios may serve as indicators of prenatal testosterone exposure.

Purpose of the Study:

  • To investigate the association between the right-hand digit length ratio (2D:4D) and prostate cancer risk.
  • To determine if finger length patterns can serve as a predictive marker for prostate cancer.

Main Methods:

  • A case-control study involving 1524 prostate cancer cases and 3044 population-based controls.
  • Analysis focused on the right-hand digit length pattern (2D:4D ratio).

Main Results:

  • Men with a higher 2D:4D ratio (index finger longer than ring finger) exhibited a 33% reduction in prostate cancer risk (OR 0.67).
  • A significant risk reduction of 87% was observed in men under 60 with a higher 2D:4D ratio (OR 0.13).

Conclusions:

  • The pattern of finger lengths, specifically the 2D:4D ratio, may function as a simple biomarker for prostate cancer risk.
  • A higher 2D:4D ratio is suggestive of a lower risk of prostate cancer.