Related Experiment Video
Updated: Jun 6, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Ehlers-Danlos syndrome associated with cleft lip and palate
Pearlie Ww Tan1, Colin Song, Donald Lalonde
1Plastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, Singapore;
Abstract:
Ehlers-Danlos syndrome (EDS) is a hereditary connective tissue disorder caused by abnormal collagen synthesis and presents with classic features of hyperextensibility, fragility of skin and joint hypermobility. It has not been commonly described as being associated with cleft lip and/or palate, and a literature search has disclosed only one case (1984) of type IV EDS with cleft lip and palate. The authors have seen another case of EDS associated with cleft lip and palate. The etiology and clinical features of this syndrome are discussed alongside the clinical picture of cleft lip and palate.
Related Concept Videos
Esophageal Achalasia
Desmosomes
Hiatal Hernia
Barrett Esophagus-I: Introduction
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more similar...
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus.

