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New coumarin-hemiterpene ether glucosides and a structurally related phenylpropanoic acid derivative from Artemisia
Mahdi Mojarrab1, Abbas Delazar, Matthias Hamburger
1Drug Applied Research Center and School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract:
Two new coumarin-hemiterpene ether glucosides, 4'-O-(beta-D-glucopyranosyl) desoxylacarol (1), and 5-O-(beta-D-glucopyranosyl) lacarol (2), were isolated from the methanolic extract of the aerial parts of Artemisia armeniaca Lam. Their structures were established by means of spectroscopic analysis including 1H- and 2D-NMR, HRESIMS, and acid hydrolysis. In addition, a structurally related phenylpropanoic acid derivative (3) was obtained in small amounts, and its structure tentatively assigned as 3-(4-hydroxy-3-methylbutoxy)-4-methoxy melilotic acid.
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