The genetic basis of spondyloarthritis: SPARTAN/IGAS 2009
David M Evans1, John D Reveille, Matthew A Brown
1University of Bristol, Bristol, UK.
Abstract:
A joint meeting was held in July 2009 in Houston, Texas, of members of the Spondyloarthritis Research and Therapy Network (SPARTAN), founded in 2003 to promote research, education, and treatment of ankylosing spondylitis (AS) and related forms of spondyloarthritis (SpA), and members of International Genetics of AS (IGAS), founded in 2003 to encourage and coordinate studies internationally in the genetics of AS. The general topic was the genetic basis of SpA, with presentations on the future of human genetic studies; microbes, SpA, and innate immunity; susceptibility of AS to the major histocompatibility complex (MHC) and non-MHC; and individual discussions of the genetics of psoriasis and psoriatic arthritis, uveitis, inflammatory bowel disease, and enteropathic arthritis. Summaries of those discussions are presented.
Related Concept Videos
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
The JAK-STAT Signaling Pathway
Single Nucleotide Polymorphisms-SNPs
Incomplete Dominance
Principles of Pharmacogenetics: Types of Genetic Variants
Inflammatory Bowel Disease III: Crohn's Disease
