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Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome
Published on: July 28, 2023
Intestinal mucormycosis in a neonate: A case report and review
1Department of Pediatric Surgery, Maulana Azad Medical College, New Delhi - 110 002, India.
Abstract:
Mucormycosis is a fungal disease that may rarely invade the gastrointestinal tract of newborn, resulting in high morbidity and mortality. Clinically, it may be indistinguishable from the neonatal necrotizing enterocolitis and the diagnosis is usually made on autopsy or histopathology of excised surgical specimen. We report a neonatal survivor of the illness.
Insights
A rare fungal infection, mucormycosis, can affect newborns' gastrointestinal tracts, posing significant risks. This report details a rare case of a neonatal survivor, offering insights into this severe condition.
Area of Science:
- Mycology
- Neonatal Medicine
- Infectious Diseases
Background:
- Mucormycosis is a rare but severe fungal infection.
- Gastrointestinal mucormycosis in neonates is associated with high morbidity and mortality.
- Clinical presentation can mimic necrotizing enterocolitis, complicating early diagnosis.
Observation:
- This case report details a rare instance of neonatal gastrointestinal mucormycosis.
- The diagnosis was confirmed post-mortem or via histopathology in typical cases.
- This report focuses on a survivor of this critical neonatal illness.
Findings:
- The study highlights a rare case of neonatal gastrointestinal mucormycosis.
- Early diagnosis remains challenging due to overlapping symptoms with necrotizing enterocolitis.
- Successful management and survival in a neonatal case are presented.
Implications:
- This case may inform diagnostic and treatment strategies for neonatal mucormycosis.
- Understanding this rare condition can improve outcomes for affected newborns.
- Further research into neonatal fungal infections is warranted.
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