Related Experiment Video
Updated: Jun 6, 2026

The bm12 Inducible Model of Systemic Lupus Erythematosus (SLE) in C57BL/6 Mice
Published on: November 1, 2015
Juvenile systemic lupus erythematosus in a adolescent with acquired immunodeficiency syndrome
Nathália de Carvalho Sacilotto1, Cintia Yukimi Yamashiro, Teresa Maria Isaac Nishimoto
1Centro Universitário Lusíada, Santos, SP, Brazil. nath-cs@uol.com.br
Abstract:
Systemic lupus erythematosus juvenile (SLEJ) is a multi-systemic, chronic inflammatory disease, and with autoimmune features. Some clinical manifestations of this disease are similar to those found in Acquired Immunodeficiency Syndrome (AIDS). Coexistence of AIDS with SLEJ is rare, especially in the pediatric population, being described in the literature just 5 patients with congenital HIV infection who developed this rheumatological condition, presenting lupus nephritis as the initial manifestation. We report the case of a 14 year old patient, diagnosed with HIV infection at 8 months of age, with signs and symptoms of SLEJ. This report aims to describe a female patient with AIDS who developed SLE in its classic and forms, but has evolved satisfactorily.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
Cytomegalovirus Disease
Autoimmune Disorders
Concept and Mechanism of Autoimmune Diseases
The immune system...
Leishmaniasis
Primary Lymphoid Organs
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
