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Oogenesis

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...

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Related Experiment Video

Updated: Jun 6, 2026

Windowing Chicken Eggs for Developmental Studies

Windowing Chicken Eggs for Developmental Studies

Published on: October 1, 2007

Egg sharing for assisted conception: a window on oocyte quality.

Malcolm Faddy¹, Roger Gosden, Kamal Ahuja

¹Mathematical Sciences, Queensland University of Technology, Brisbane, Australia.

Reproductive Biomedicine Online

|December 4, 2010

Summary

This summary is machine-generated.

Egg sharing programs demonstrate that donor pregnancy predicts recipient pregnancy, highlighting oocyte quality

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Last Updated: Jun 6, 2026

Windowing Chicken Eggs for Developmental Studies

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Published on: October 1, 2007

Human Egg Maturity Assessment and Its Clinical Application

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Published on: August 19, 2019

Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes

Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes

Published on: May 11, 2017

Area of Science:

Reproductive Medicine
Human Embryology

Background:

Maternal age significantly impacts natural fertility and assisted reproduction success.
Oocyte developmental competence varies considerably and is age-dependent.
Egg sharing programs offer donated oocytes to patients needing them, allowing outcome comparison.

Purpose of the Study:

To evaluate the significance of oocyte quality in egg sharing programs.
To compare reproductive outcomes between egg providers and recipients.

Main Methods:

Analysis of data from 285 egg sharing provider-recipient pairs across two treatment centers.
Statistical comparison of pregnancy rates between providers and recipients.

Main Results:

Donor pregnancy was a significant predictor of recipient pregnancy (OR 2.15, P ≈ 0.002).
Recipient pregnancy probability increased by approximately 0.2.
These results held despite recipients being older on average.

Conclusions:

Oocyte quality is a critical factor for successful outcomes in egg sharing.
The findings underscore the importance of oocyte quality in assisted reproduction treatments generally.