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Updated: Jun 6, 2026

Temporal Quantification of MAPK Induced Expression in Single Yeast Cells
Published on: October 4, 2013
Defining MAPK interactomes
1Department of Pharmacology, University of North Carolina, Chapel Hill, 27599, United States. glj@med.unc.edu
Abstract:
The mitogen-activated protein kinase (MAPK) signaling network is integrated into most, if not all, defined homeostatic and regulatory responses of eukaryotic cells. A systematic experimental and computational approach has been used to identify more than 2,000 protein interactions related to functions and regulation of the MAPK signaling network. This discovery process provides a rich data and reagent resource for defining complexities of protein networks involving MAPKs and control of cellular physiology.
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