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Related Concept Videos

Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
mTOR Signaling and Cancer Progression03:03

mTOR Signaling and Cancer Progression

The mammalian target of rapamycin or mTOR protein was discovered in 1994 due to its direct interaction with rapamycin. The protein gets its name from a yeast homolog called TOR. The mTOR protein complex in mammalian cells plays a major role in balancing anabolic processes such as the synthesis of proteins, lipids, and nucleotides and catabolic processes, such as autophagy in response to environmental cues, such as availability of nutrients and growth factors.
The mTOR pathway or the...
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...

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Randomized open-label controlled study of cancer vaccine OSE2101 versus chemotherapy in HLA-A2-positive patients with advanced non-small-cell lung cancer with resistance to immunotherapy: ATALANTE-1.

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The role of patient-reported outcome measures in the continuum of cancer clinical care: ESMO Clinical Practice Guideline.

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[Radiation-oncology horizon 2030: From microbiota to plasma laser].

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[New concepts of medical consultation in oncology].

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[Immunity and antiviral vaccinations. Example: the respiratory mucosa].

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Meningococcal C vaccine coverage in France in infants, children, and adolescents.

Medecine et maladies infectieuses·2019
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Related Experiment Video

Updated: Jun 6, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
09:48

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

[Endometrial cancer].

Y Pointreau1, G Bernadou, F Denis

  • 1Service de radiothérapie, centre régional universitaire de cancérologie Henry-S.-Kaplan CHU de Tours, Hôpital Bretonneau, 2 Boulevard Tonnellé, 37000 Tours, France.

Cancer Radiotherapie : Journal De La Societe Francaise De Radiotherapie Oncologique
|December 7, 2010
PubMed
Summary
This summary is machine-generated.

Endometrial cancer management for postmenopausal women involves surgery for precise staging. Treatment strategies for early and advanced stages, including radiotherapy, are guided by risk factors and tumor characteristics.

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Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
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Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Related Experiment Videos

Last Updated: Jun 6, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
09:48

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells

Published on: September 12, 2019

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Area of Science:

  • Gynecology
  • Oncology
  • Radiation Oncology

Context:

  • Endometrial cancer is a common malignancy primarily affecting postmenopausal women.
  • Early-stage diagnosis often leads to an excellent prognosis.
  • Surgical staging is crucial for guiding adjuvant treatment decisions.

Purpose:

  • To outline current management strategies for endometrial cancer.
  • To discuss the role of surgery, radiotherapy, and chemotherapy in different stages.
  • To illustrate radiotherapy indications, planning, and potential complications through a clinical case.

Summary:

  • Surgery provides precise FIGO staging for endometrial cancer, informing therapeutic strategies based on tumor extension, grade, myometrial invasion, and lymph node involvement.
  • Management of early-stage (I and II) disease involves risk stratification (low, intermediate, high) with options including surveillance, brachytherapy, or radiation therapy followed by brachytherapy, though recommendations require confirmation.
  • Locally advanced stages, a heterogeneous group, are managed with feasible surgery followed by radiotherapy and/or chemotherapy, with radiotherapy details elucidated via a clinical case.

Impact:

  • Provides a comprehensive overview of endometrial cancer treatment paradigms.
  • Highlights the evolving recommendations for early-stage disease management.
  • Offers practical insights into radiotherapy application for advanced endometrial cancer.