Related Experiment Video

Updated: Jun 6, 2026

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
05:41

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

Primary percutaneous coronary intervention for patients presenting with ST-segment elevation myocardial infarction:

Nathaniel W Niles1, Sheila M Conley, Rayson C Yang

  • 1Section of Cardiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.nat.niles@hitchcock.org

Progress in Cardiovascular Diseases
|December 7, 2010
PubMed

Insights

Rural hospitals improved ST-segment elevation myocardial infarction (STEMI) care by implementing evidence-based strategies. This led to faster electrocardiogram (ECG) and door-to-balloon (D2B) times for STEMI patients.

Area of Science:

  • Cardiology
  • Healthcare Management
  • Emergency Medicine

Background:

  • Rural ST-segment elevation myocardial infarction (STEMI) networks face challenges in meeting the guideline-recommended door-to-balloon (D2B) time of ≤90 minutes.
  • The ST-ELEVATION MYOCARDIAL INFARCTION PROCESS UPGRADE PROJECT aimed to enhance STEMI care in a rural setting.

Purpose of the Study:

  • To implement and evaluate evidence-based strategies to reduce time to electrocardiogram (ECG) and D2B in rural STEMI patients.
  • To assess the impact of process improvements on acute myocardial infarction care delivery.

Main Methods:

  • A multidisciplinary team at a rural percutaneous coronary intervention (PCI) center implemented strategies including prehospital ECG activation, single-call lab activation, and a ≤30-minute lab response time.
  • Data on process time intervals (time to ECG, D2B) were collected from a regional STEMI registry for patients before (group 1) and after (group 2) strategy implementation.

Main Results:

  • Group 2 demonstrated significant reductions in the time to the first ECG in the emergency department compared to group 1.
  • A significant decrease in door-to-balloon (D2B) times was observed in group 2 following the implementation of the new strategies.

Conclusions:

  • Evidence-based strategies effectively improved the acute STEMI patient care process in a rural PCI center.
  • The project successfully reduced critical time intervals, enhancing outcomes for STEMI patients in a resource-limited setting.
Abstract

More Related Videos

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction05:26

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

Published on: May 28, 2019

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...