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Updated: Jun 6, 2026

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

[Candida peritonitis]

Alejandro Ubeda1, Ana Loza Vázquez, Cristóbal León Gil

  • 1Hospital Universitario de Valme, Sevilla, España. alejandroubedaintensivos@hotmail.com

Enfermedades Infecciosas Y Microbiologia Clinica
|December 7, 2010
PubMed

Insights

Distinguishing Candida infection from colonization in abdominal infections is challenging. Clinical signs like sepsis or repeated isolation often prompt antifungal treatment, similar to other invasive Candida infections.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Candida species are part of the normal digestive tract flora.
  • Candida can cause abdominal infections, particularly secondary peritonitis after intestinal surgery.
  • Differentiating Candida colonization from infection in peritoneal fluid is clinically significant.

Purpose of the Study:

  • To review the diagnostic challenges of Candida isolation in abdominal infections.
  • To discuss criteria for initiating antifungal therapy in such cases.

Main Methods:

  • Review of current clinical recommendations and practices.
  • Analysis of factors influencing the interpretation of Candida cultures from peritoneal fluid.

Main Results:

  • No consensus exists on interpreting Candida isolation in peritoneal drainage fluid.
  • Intraoperative or directly collected samples are more indicative of infection.
  • Repeated isolation, sepsis signs, or severity criteria often lead to antifungal treatment.

Conclusions:

  • Clinical context is crucial for interpreting Candida isolation in abdominal infections.
  • Antifungal therapy decisions are guided by signs of invasive disease, similar to candidemia.
  • Standardized guidelines are needed for managing Candida in peritoneal infections.

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