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Ghrelin promotes nuclear factor kappa-B activation in a human B-lymphocyte cell line

E Z H Sung1, N F Da Silva, S J Goodyear

  • 1Department of Gastroenterology, University Hospital of Coventry, Coventry, CV2 2DX, UK.

Molecular Biology Reports
|December 7, 2010
PubMed
Summary

Octanoyl ghrelin, a gastric hormone, activates NFκB (nuclear factor kappa B) in human B-lymphocytes, suggesting a role in modulating inflammation. This study found increased NFκB activity with octanoyl ghrelin treatment.

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