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[Ambulatory blood pressure measurement and control in hypertensive diabetic patients]
Faouzi Kanoun1, Nefissa Ben Alaya, Salma Idriss
1Service d'Endocrinologie-Diabétologie, Hôpital La Rabta, Tunis, Jabbary, Tunisia.
Insights
Most treated diabetic patients with hypertension struggle with blood pressure control. Ambulatory blood pressure monitoring revealed that a loss of nocturnal blood pressure dip is linked to poor control and increased microangiopathy risk.
Area of Science:
- Cardiology
- Endocrinology
- Nephrology
Context:
- Effective blood pressure (BP) management is crucial for diabetic patients.
- Hypertension is a common comorbidity in diabetes mellitus.
- Suboptimal BP control in diabetics increases the risk of cardiovascular and microvascular complications.
Purpose:
- To assess BP control in hypertensive diabetic individuals using 24-hour ambulatory blood pressure monitoring (ABPM).
- To identify factors associated with poor BP control in this patient cohort.
Summary:
- A study of 206 hypertensive treated diabetic patients using ABPM found only 13.6% achieved target BP levels.
- Poor BP control was significantly associated with non-dipper BP patterns, diabetic nephropathy, and diabetic retinopathy.
- The loss of nocturnal BP dipping was the primary abnormality linked to inadequate BP management.
Impact:
- Highlights the widespread issue of poor BP control among treated hypertensive diabetics.
- Emphasizes the diagnostic value of ABPM in identifying BP control deficits.
- Suggests that targeting nocturnal BP patterns may improve outcomes and reduce microvascular complications in diabetic patients.
Background:
Good blood pressure control is one of the recommended targets in diabetic patient's management.
Aim:
To evaluate blood pressure (BP) control in hypertensive treated diabetic patients using ambulatory blood pressure measurement (ABPM).
Methods:
Two hundred and six hypertensive treated diabetic patients were enrolled in this study (83 men and 123 women). Mean age were 60.3±9.6 years-old with mean diabetic duration of 9.1±8.2 years. All of them underwent 24 hours ABPM. Intervals between measurements were 20 minutes at diurnal period and 30 minutes at nocturnal period.
Results:
28 patients (13.6%) only were at recommended target levels of blood pressure control (mean diurnal BP<130/80 mmHg and nocturnal BP<115/65 mmHg) and 137 patients were at the most bed control levels (mean diurnal BP ? 140/90 mmHg or nocturnal BP ? 125/75 mmHg). Bed controlled patients had mildly higher waist circumference (p=0.08). Poor BP control was associated with non dipper character (p<0.001), diabetic nephropathy (p<0.01) and diabetic retinopathy (p<0.01).
Conclusion:
Our hypertensive treated diabetic patients were far from good blood pressure control. ABPM showed that the loss of nocturnal blood pressure fall was the most associated abnormality with poor BP control. Diabetic microangiopathy were more frequent in poor controlled patients.
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