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Related Concept Videos

Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Standard Precaution01:26

Standard Precaution

Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...

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Related Experiment Videos

Preventing Staphylococcus infections in high-risk patients.

S T Bailey1, J J Cullen

  • 1Medical Student, University of Iowa College of Medicine, Iowa City, IA.

Surgical Technology International
|December 8, 2010
PubMed
Summary

Surgical site infections (SSIs) affect up to 30% of patients, increasing complications and costs. Prior nasal carriage of Staphylococcus species is a significant risk factor for developing these infections post-surgery.

Area of Science:

  • Infectious Diseases
  • Surgical Outcomes
  • Microbiology

Background:

  • Surgical site infections (SSIs) are a common complication following surgical procedures.
  • SSIs lead to increased patient morbidity, prolonged hospital stays, and elevated healthcare costs.
  • Staphylococcus species are frequently implicated in the etiology of SSIs.

Purpose of the Study:

  • To highlight the incidence and impact of surgical site infections.
  • To identify Staphylococcus species as key pathogens in SSIs.
  • To underscore the role of pre-operative nasal carriage as a risk factor for post-surgical infection.

Main Methods:

  • Literature review and synthesis of existing data on SSI prevalence.
  • Analysis of etiological agents responsible for SSIs.

Related Experiment Videos

  • Examination of risk factors associated with SSI development, focusing on nasal carriage.
  • Main Results:

    • Up to 30% of surgical patients are at risk of developing SSIs, with incidence varying by procedure.
    • Staphylococcus species are a major cause of SSIs.
    • Pre-operative nasal carriage of Staphylococcus species is a confirmed risk factor for post-surgical infection.

    Conclusions:

    • Reducing SSI rates is crucial for improving surgical outcomes and managing healthcare resources.
    • Targeting Staphylococcus nasal carriage may offer a strategy for SSI prevention.
    • Further research into decolonization strategies could mitigate SSI risk.