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Management of infection in the surgical patient
1Research Fellow, Division of General Surgery, University of Toronto, Toronto, Canada.
Abstract:
While surgical infections are seemingly a heterogeneous group of disease entities, there are several common features that permit a general approach to their diagnosis and management. These properties include: the polymicrobial nature of the flora in most infections, the association of the infection with some underlying pathological process, and appropriate treatment often includes both broad-spectrum antimicrobial therapy and some surgical or radiological intervention to promote eradication of the infection. For the purpose of this review, intra-abdominal infection will be used as the prototypical surgical infection because it embodies many of the general features of most infections.
Insights
Surgical infections, often polymicrobial and linked to underlying pathology, require broad-spectrum antibiotics and surgical intervention. Intra-abdominal infections serve as a model for understanding these common diagnostic and management principles.
Area of Science:
- Surgical infections
- Infectious disease management
Background:
- Surgical infections present diverse clinical pictures.
- Common features facilitate a generalized diagnostic and management strategy.
Purpose of the Study:
- To outline a general approach to the diagnosis and management of surgical infections.
- To use intra-abdominal infections as a representative model.
Main Methods:
- Review of common features of surgical infections.
- Utilizing intra-abdominal infections as a prototypical example.
Main Results:
- Most surgical infections are polymicrobial.
- Infections are associated with underlying pathological processes.
- Treatment typically involves broad-spectrum antimicrobials and surgical/radiological intervention.
Conclusions:
- A unified approach to surgical infection diagnosis and management is feasible.
- Intra-abdominal infections exemplify key characteristics of surgical infections.
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