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Updated: Jun 6, 2026
08:32
Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
[Dysphagia in the elderly: which drugs are crushable?]
Jérôme Vallat1, Nadège Barro-Belaygues, Zoubeir Ramjaun
1Centre Hospitalier de Montauban. j.vallat@ch-montauban.fr
Soins. Gerontologie
|December 9, 2010
Summary
Elderly patients with swallowing difficulties often require medication modifications, which can pose risks. This article reviews drug transformations, considering their pharmacological and clinical properties for safe administration.
Area of Science:
- Geriatric Medicine
- Clinical Pharmacy
- Pharmacology
Context:
- Deglutition disorders (dysphagia) are common in the elderly population.
- Medication administration in elderly patients with dysphagia often necessitates formulation modifications.
- Altering drug dosage forms, such as crushing tablets or opening capsules, carries inherent risks.
Purpose:
- To identify and discuss medications that can be safely modified for elderly patients with swallowing difficulties.
- To analyze the pharmacological and clinical characteristics of various drugs concerning potential transformations.
- To provide guidance on appropriate medication management for geriatric patients with dysphagia.
Summary:
- This article examines the safety and efficacy of modifying drug formulations for elderly individuals experiencing swallowing impairments.
- It details specific drugs and their susceptibility to transformation, considering factors like bioavailability and therapeutic effect.
- The review highlights potential risks associated with altering dosage forms.
Impact:
- Enhances safe medication practices for geriatric patients with dysphagia.
- Supports healthcare professionals in making informed decisions regarding drug administration.
- Contributes to improved therapeutic outcomes and reduced adverse events in elderly populations with swallowing disorders.
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