Related Experiment Video
Updated: Jun 6, 2026
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Association between chronic periodontitis and serum lipid levels
Ferial Taleghani1, Mahmoud Shamaei, Masoud Shamaei
1Department of Periodontics, School of Dentistry, Shahed University, Tehran, Iran.
Acta Medica Iranica
|December 9, 2010
Summary
Chronic periodontitis patients showed higher triglyceride and abnormal cholesterol levels compared to healthy individuals. Further research is needed to understand the impact of periodontitis treatment on serum lipid profiles.
Area of Science:
- Cardiovascular Health
- Periodontology
- Biochemistry
Background:
- Hyperlipidemia is a significant risk factor for cardiovascular disease.
- The relationship between periodontal disease and serum lipid profiles requires further investigation.
Purpose of the Study:
- To assess the association between chronic periodontitis and serum lipid profiles.
- To investigate potential links between periodontal disease and hyperlipidemia.
Main Methods:
- A historical cohort study involving 52 participants (26 with chronic periodontitis, 26 healthy controls).
- Controlled for age, weight, sex, diet, and excluded participants with prior treatment, systemic diseases, or smoking.
- Measured Low Density Lipoprotein (LDL), High Density Lipoprotein (HDL), Triglyceride (TG), and Total Cholesterol (CHOL) using direct enzymatic assay.
Main Results:
- Significantly higher triglyceride levels (165.2 +/- 83.7 mg/dl) in the periodontitis group compared to the control group (128.4 +/- 71.1 mg/dl, P<0.05).
- A higher prevalence of abnormal serum cholesterol levels (61.5%) in the periodontitis group versus the control group (30.8%, P<0.03).
- No significant differences were observed in other serum lipid indices.
Conclusions:
- Patients with chronic periodontitis may be more susceptible to hyperlipidemia.
- The causal relationship between periodontitis and elevated serum lipid levels remains uncertain.
- Investigating the effect of treating chronic periodontitis on serum lipid levels is recommended.
Related Concept Videos
01:25Blood Studies for Cardiovascular System III: Serum Lipid Profile
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
01:27The Oral Microbiota
The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
01:24Chronic Pancreatitis I: Introduction
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
01:25Chronic Pancreatitis I: Introduction
Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
01:24Chronic Kidney Disease II: Clinical Manifestations
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
01:21Chronic Pancreatitis II: Pathophysiology
Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...