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Fluorescence-quenching of a Liposomal-encapsulated Near-infrared Fluorophore as a Tool for In Vivo Optical Imaging
Published on: January 5, 2015
Fluorescence thermal antiquenching of liposome encapsulated CdSe quantum dots
Qinghui Zeng1, Youlin Zhang, Yajuan Sun
1Key Laboratory of Excited State Processes, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, 3888 Eastern South Lake Road, Changchun 130033, China.
Abstract:
The green emission semiconductor CdSe quantum dots are successfully encapsulated with lecithoid molecules and transferred into aqueous solution. The liposome-encapsulated CdSe maintain similar emission spectrum properties to free CdSe quantum dots. Fluorescence thermal antiquenching is investigated for the liposome-encapsulated CdSe when the temperature is increased from 20 degrees C to 80 degrees C. The reason of the fluorescence enhancement with increasing the temperature is that the vesicle structure of liposome-encapsulated CdSe becomes the CdSe micell structure over the phase transition temperature of the liposome vesicles, and the corresponding structure variation inducing surface reconstruction of CdSe quantum dots.
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