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Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...

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Related Experiment Video

Updated: Jun 6, 2026

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome
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Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

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[Ventricular diastolic dysfunction in rheumatoid arthritis].

C Lascano1, Paula Alba, C Gobbi

  • 1Unidad de Reumatología y Ecocardiografía Hospital, Córdoba, Argentina.

Revista De La Facultad De Ciencias Medicas (Cordoba, Argentina)
|December 9, 2010
PubMed
Summary

Rheumatoid arthritis patients often have impaired diastolic function, a subclinical heart issue. This study found no link between disease duration and diastolic dysfunction in rheumatoid arthritis (RA) patients.

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Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism
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Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

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Last Updated: Jun 6, 2026

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome
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Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

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Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism
11:04

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

Area of Science:

  • Cardiology
  • Rheumatology
  • Internal Medicine

Background:

  • Rheumatoid arthritis (RA) is a systemic inflammatory disease with potential cardiac manifestations.
  • Cardiac involvement in RA can be asymptomatic and is linked to increased mortality.
  • Diastolic dysfunction is an early indicator of cardiac disease in RA patients.

Purpose of the Study:

  • To evaluate ventricular diastolic dysfunction in patients with rheumatoid arthritis (RA).
  • To investigate the relationship between the duration of RA and the presence of diastolic dysfunction.

Main Methods:

  • Echocardiography (2D, M-mode, pulsed, and color Doppler) was performed on 32 RA patients and 32 healthy controls.
  • Diastolic dysfunction was defined by E/A ratio < 1 and prolonged deceleration time (DT) and isovolumic relaxation time (IRT).
  • Exclusion criteria included diabetes, hypertension, lung disease, and other cardiac conditions.

Main Results:

  • RA patients showed a significantly higher proportion of E/A ratio < 1 compared to controls (p<0.0001).
  • The mean isovolumic relaxation time (IRT) was significantly longer in RA patients (83.59 ± 13.82 vs. 74.41 ± 15.14, p<0.01).
  • No significant correlation was found between disease duration and E/A ratio or IRT (p=0.70, p=0.13).

Conclusions:

  • Diastolic function is impaired in patients with rheumatoid arthritis.
  • No relationship was observed between disease duration and key parameters of ventricular diastolic function.
  • These findings suggest subclinical myocardial involvement in RA patients.