Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Response01:28

Inflammatory Response

An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammation01:38

Inflammation

Overview
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Long COVID clinical evaluation, research and impact on society: a global expert consensus.

Annals of clinical microbiology and antimicrobials·2025
Same author

Long COVID clinical evaluation, research and impact on society: a global expert consensus.

Annals of clinical microbiology and antimicrobials·2025
Same author

Re: Brown, Sharma, Ardern, et al., Secular changes in the association between caloric intake, macronutrient intake and physical activity with obesity.

Obesity research & clinical practice·2016
Same author

The gut microbiome and the brain.

Journal of medicinal food·2014
Same author

Mechanisms of behavioral, atopic, and other reactions to artificial food colors in children.

Nutrition reviews·2013
Same author

Antioxidants and chemotherapy.

Alternative therapies in health and medicine·2007

Related Experiment Video

Updated: Jun 6, 2026

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
09:04

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat

Published on: February 27, 2014

Diet and inflammation.

Leo Galland1

  • 1Foundation for Integrated Medicine, New York, NY 10010, USA. lgallandmd@aol.com

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition
|December 9, 2010
PubMed
Summary

Diet significantly influences chronic inflammation markers. The Mediterranean diet, rich in fruits, vegetables, and healthy fats, shows anti-inflammatory effects compared to Western diets, potentially aiding in managing degenerative diseases.

Area of Science:

  • Nutrition science
  • Immunology
  • Preventive medicine

Background:

  • Chronic inflammation is linked to major degenerative diseases.
  • Nutrition and dietary patterns are being investigated for their impact on inflammatory markers.
  • Systemic inflammation markers include high-sensitivity C-reactive protein (HS-CRP), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-α).

Purpose of the Study:

  • To review the influence of nutrition and dietary patterns on inflammatory indices.
  • To evaluate the effects of dietary changes on inflammatory markers in defined populations.
  • To highlight the anti-inflammatory potential of the Mediterranean diet.

Main Methods:

  • Correlational analyses of habitual dietary intake using food frequency questionnaires or 24-hour recalls.

More Related Videos

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
08:58

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

Published on: January 5, 2017

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

Related Experiment Videos

Last Updated: Jun 6, 2026

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
09:04

DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat

Published on: February 27, 2014

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis
08:58

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

Published on: January 5, 2017

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
12:50

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response

Published on: September 15, 2017

  • Controlled intervention studies evaluating dietary pattern changes or single food effects on inflammatory markers.
  • Analysis of nutrition in blood components in some studies.

    • Main Results:

    • Dietary composition has a modest effect on some inflammatory markers in free-living adults.
    • Specific nutrients like fiber, fatty acids, magnesium, carotenoids, and flavonoids show significant influence.
    • The Mediterranean diet demonstrates anti-inflammatory effects compared to North American and Northern European diets.

    Conclusions:

    • Dietary patterns play a role in modulating chronic inflammation.
    • The Mediterranean diet is a promising dietary approach for reducing chronic inflammation.
    • Further research supports the Mediterranean diet for clinical practice in managing inflammation-related diseases.