Related Experiment Video
Updated: Jun 6, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
A legacy of tinnitus: multiple head and neck paragangliomas
Tricia M M Tan1, Emma C I Hatfield, Rajesh V Thakker
1Department of Investigative Medicine, Division of Investigative Science, Imperial Healthcare NHS Trust, London, UK;
Abstract:
We describe the case of a patient who presented with a right-sided glomus jugulare tumor and bilateral glomus vagale tumors. These proved to be nonmalignant paragangliomas on histopathological analysis. Genetic analysis revealed a germline heterozygous missense mutation (Pro81Leu) in the succinate dehydrogenase subunit D (SDHD) gene. We discuss the clinical presentations of the familial paraganglioma syndrome type 1, which is caused by mutations in SDHD, and the implications for the clinical diagnosis and care of such patients.
Related Concept Videos
Cranial Part of Parasympathetic Division
The vagus nerve (cranial nerve X) alone accounts for approximately 75...
Veins of Head and Neck
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Arteries of the Head and Neck
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
Sympathetic Pathways: Sympathetic Chain Ganglia
