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Related Concept Videos

Herpes01:28

Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
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Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Chickenpox01:20

Chickenpox

Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
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Angle Closure Glaucoma: Treatment

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Related Experiment Video

Updated: Jun 6, 2026

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
07:55

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection

Published on: November 3, 2012

Herpes simplex keratitis -- an unusual clinical presentation.

S K Arya1, C Malhotra, R Bhatia

  • 1Department of Ophthalmology, Government Medical College, Sector 32, Chandigarh-160030, India. aryasudesh@yahoo.co.in

Nepalese Journal of Ophthalmology : a Biannual Peer-Reviewed Academic Journal of the Nepal Ophthalmic Society : NEPJOPH
|December 15, 2010
PubMed
Summary
This summary is machine-generated.

A young patient developed a rare posterior corneal abscess extending into the anterior chamber, presumed to be herpes simplex keratitis. Prompt treatment with acyclovir led to a positive outcome, highlighting an unusual ocular herpes presentation.

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Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
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Last Updated: Jun 6, 2026

Ex Vivo Organotypic Corneal Model of Acute Epithelial Herpes Simplex Virus Type I Infection
07:55

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Published on: November 3, 2012

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Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

Published on: December 18, 2012

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Virology

Background:

  • Herpes simplex keratitis (HSK) typically affects the corneal epithelium or stroma.
  • Posterior segment involvement in HSK is less common, especially without epithelial defects.

Observation:

  • A case is presented of a young patient with a posterior corneal abscess and anterior chamber extension.
  • This occurred despite intact corneal epithelium and clear anterior corneal stroma.
  • The clinical presentation mimicked other intraocular infections.

Findings:

  • The patient was diagnosed with presumed herpes simplex keratitis.
  • Treatment with systemic and topical acyclovir resulted in a favorable response.
  • This represents an unusual manifestation of ocular herpes.

Implications:

  • This case expands the spectrum of clinical presentations for herpes simplex keratitis.
  • It underscores the importance of considering viral etiologies in atypical corneal and anterior chamber abscesses.
  • Early diagnosis and antiviral treatment are crucial for managing such unusual ocular infections.