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Updated: Jun 6, 2026

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Solubility of Hydrophobic Compounds in Aqueous Solution Using Combinations of Self-assembling Peptide and Amino Acid
Published on: September 20, 2017
Water-soluble peptide-coated nanoparticles: control of the helix structure and enhanced differential binding to
Iria M Rio-Echevarria1, Regina Tavano, Valerio Causin
1Dipartimento di Scienze Chimiche, Università di Padova, via Marzolo 1, 35131 Padova, Italy.
Journal of the American Chemical Society
|December 15, 2010
Abstract:
The stabilizing action of C(α)-tetrasubstituted α-amino acids inserted into a sequence of short peptides allowed for the first time the preparation of water-soluble nanoparticles of different materials coated with a helix-structured undecapeptide. This peptide coating strongly favors nanoparticle uptake by human immune system cells.

