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Updated: Jun 6, 2026
12:45
Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Criteria for patient selection in cardiac resynchronization therapy
Oliver Turschner1, Guido Ritscher, Helge Simon
1Department of Cardiology, Klinikum Coburg, Germany, Medizinische Klinik II, Klinikum Coburg, Ketschendorfer Str. 33, 96450 Coburg, Germany.
Future Cardiology
|December 15, 2010
Summary
Cardiac resynchronization therapy (CRT) improves heart failure outcomes, but patient selection is key. This review summarizes CRT patient selection methods to optimize treatment success and reduce therapy costs.
Area of Science:
- Cardiology
- Medical Devices
Background:
- Cardiac resynchronization therapy (CRT) has improved prognosis in severe heart failure patients by reducing morbidity and mortality.
- However, a significant portion of patients do not benefit from CRT, or even experience deterioration.
Purpose of the Study:
- To provide an overview of CRT and summarize patient selection parameters.
- To highlight limitations in current CRT patient selection methods.
- To aid clinical decision-making for CRT by reviewing guidelines and potential new indications.
Main Methods:
- Review of multicenter trials and existing publications on CRT patient selection.
- Analysis of various methods for predicting positive or negative CRT response.
- Focus on current guidelines for CRT indication and device programming.
Main Results:
- Despite CRT's benefits, suboptimal patient selection and device programming contribute to treatment failure.
- Numerous predictive methods exist, but often yield contradictory results, necessitating clear guidelines.
- Current guidelines and selection parameters require refinement to optimize CRT outcomes.
Conclusions:
- Improved patient selection is crucial for enhancing the effectiveness of cardiac resynchronization therapy.
- A comprehensive understanding of selection parameters and adherence to guidelines can improve CRT success rates.
- Further research into new indications and refined selection criteria is warranted.
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