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Updated: Jun 6, 2026

Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology
Published on: March 27, 2018
Regenerative medicine of the kidney
Laura Perin1, Stefano Da Sacco, Roger E De Filippo
1Division of Urology, Saban Research Institute, Developmental Biology Program, Childrens Hospital Los Angeles, 4650 Sunset Blvd MS #35, Los Angeles, CA 90027, USA. lperin@chla.usc.edu
Abstract:
End stage renal disease is a major health problem in this country and worldwide. Although dialysis and kidney transplantation are currently used to treat this condition, kidney regeneration resulting in complete healing would be a desirable alternative. In this review we focus our attention on current therapeutic approaches used clinically to delay the onset of kidney failure. In addition we describe novel approaches, like Tissue Engineering, Stem cell Applications, Gene Therapy, and Renal Replacement Therapy that may one day be possible alternative therapies for patients with the hope of delaying kidney failure or even stopping the progression of renal disease.
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