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Updated: Jun 6, 2026

Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies

Quantification of Vascular Parameters in Whole Mount Retinas of Mice with Non-Proliferative and Proliferative Retinopathies

Published on: March 12, 2022

[Vasoproliferative retinal tumours].

S Pfrommer¹, M Maier, C Mayer

¹Klinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar der Technischen Universität München, Ismaninger Strasse 22, 81675, München, Deutschland. sarah.pfrommer@googlemail.com

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft

|December 15, 2010

Summary

This summary is machine-generated.

Bartonella henselae infection can cause vasoproliferative retinal tumors, leading to vision loss. Treatment with antibiotics and cryotherapy successfully regressed the tumor and improved vision.

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Area of Science:

Ophthalmology
Infectious Diseases
Oncology

Background:

Vasoproliferative retinal tumors are benign neoplasms of unknown etiology.
These tumors are frequently associated with vitreoretinal inflammation.
The differential diagnosis for retinal tumors can be challenging.

Observation:

A case of a 21-year-old female with acute, unilateral vision reduction.
Clinical presentation included a vascularized retinal lesion, detachment, and hard exudates.
The patient exhibited an elevated Bartonella henselae titer as the sole laboratory abnormality.

Findings:

The patient was diagnosed with a vasoproliferative retinal tumor secondary to Bartonella henselae infection.
Treatment involved a course of macrolide antibiotics for the infection.
Cryotherapy was employed for direct tumor management.

Implications:

This case highlights the importance of considering infectious etiologies, such as Bartonella henselae, in the diagnosis of vasoproliferative retinal tumors.
Successful management involved a combined approach of antimicrobial therapy and local destructive treatment.
Early diagnosis and appropriate treatment can lead to favorable visual outcomes in patients with these tumors.