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In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
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Related Experiment Video

Updated: Jun 6, 2026

Genome-wide Snapshot of Chromatin Regulators and States in Xenopus Embryos by ChIP-Seq

Genome-wide Snapshot of Chromatin Regulators and States in Xenopus Embryos by ChIP-Seq

Published on: February 26, 2015

Setting up the JBrowse genome browser.

Mitchell E Skinner¹, Ian H Holmes

¹University of California at Berkeley, Berkeley, California, USA.

Current Protocols in Bioinformatics

|December 15, 2010

Summary

This summary is machine-generated.

JBrowse is a fast, smooth web-based genome browser that visualizes genomic data. It is easy to install and supports multiple common data formats for broad accessibility.

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Genome-wide Snapshot of Chromatin Regulators and States in Xenopus Embryos by ChIP-Seq

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Area of Science:

Bioinformatics
Computational Biology
Genomic Data Visualization

Background:

Genome browsers are essential tools for visualizing and analyzing genomic data.
Existing web-based genome browsers often face performance limitations in scrolling and zooming.
There is a need for efficient and user-friendly tools for exploring large-scale genomic datasets.

Purpose of the Study:

To introduce JBrowse, a novel web-based genome browser designed for high performance.
To provide a comprehensive guide for installing and configuring JBrowse on a web server.
To demonstrate how to integrate diverse genomic data formats into JBrowse for comprehensive visualization.

Main Methods:

JBrowse utilizes the user's web browser capabilities to achieve fast and smooth navigation.
The software supports common genomic data formats including GFF, BED, and wiggle files.
Installation and setup protocols are described for Linux and Mac OS X operating systems.

Main Results:

JBrowse offers significantly improved scrolling and zooming performance compared to traditional browsers.
The tool is compatible with most widely used internet browsers.
Users can integrate multiple data sources and formats for a unified genomic data exploration experience.

Conclusions:

JBrowse provides an efficient, accessible, and user-friendly platform for web-based genomic data visualization.
The ease of installation and broad data format support make JBrowse a valuable tool for researchers.
Implementing JBrowse enables the creation of shareable web sites for collaborative genomic data browsing.