[Single nucleotide polymorphisms of slow troponin T gene in Han ethnic population from Northern China]
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Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis
Published on: June 9, 2018
Chun-Yan Xu1, Yang Hu, Hai-Ping Liu
1Beijing Sports University, Section of Exercise Biochemistry, Beijing 100084, China.
Aim:
To analyze the distribution of single nucleotide polymorphisms in Han ethnic population from Northern China.
Methods:
Allele frequencies in a sample of healthy Chinese Hans (n = 204) were determined by polymerase chain reactions followed by restriction analyses with specific endonucleases.
Results:
The SNP 27916722 A/C in exon 11 from the NCBI database was not detected in this population. And there were significant differences between the allele frequencies of the SNPs (27930097 C/G and 27920978 C/T) in Han ethnic population from Northern China and those in the NCBI.
Conclusion:
It is suggested that the SNPs of sTnT are different in different ethnic populations.
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