Related Experiment Video
Updated: Jun 6, 2026

08:58
Fully Automated Centrifugal Microfluidic Device for Ultrasensitive Protein Detection from Whole Blood
Published on: April 16, 2016
Multi-parameter determination of TNFα, PCT and CRP for point-of-care testing
Petra M Krämer1, Melanie Kess, Elisabeth Kremmer
1Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Ecological Chemistry, Neuherberg, Oberschleissheim, Germany. kramer@helmholtz-muenchen.de
The Analyst
|December 16, 2010
Abstract:
A proof of concept for the simultaneous multi-parameter determination of three inflammation and sepsis parameters-TNFα, PCT and CRP-using a compact optical immunosensor is demonstrated. Harmonized assay conditions revealed standard curves with test midpoints (IC(50)) of 380 µg L(-1) for TNFα, 2300 µg L(-1) for PCT, and 2645 µg L(-1) for CRP.
