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Death from asthma in children.

T Matsui1, M Baba

  • 1Department of Pediatrics, Tokyo Metropolitan Toshima Hospital, Japan.

Acta Paediatrica Japonica : Overseas Edition
|April 1, 1990
PubMed
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Childhood asthma deaths in Japan are concerning, with many occurring rapidly and some linked to steroid withdrawal. Early, aggressive treatment is crucial for severe asthma attacks in children.

Area of Science:

  • Pediatrics
  • Respiratory Medicine
  • Epidemiology

Background:

  • Asthma is a significant cause of childhood mortality.
  • Understanding patterns of pediatric asthma deaths is crucial for public health interventions.

Purpose of the Study:

  • To analyze 29 cases of childhood asthma deaths in Japan between 1965 and 1987.
  • To identify risk factors and causes of death in pediatric asthma fatalities.

Main Methods:

  • Retrospective case review of pediatric asthma deaths at Doai Memorial Hospital.
  • Analysis of patient demographics, clinical course, and causes of death.

Main Results:

  • The mean age at death was 12.4 years, with an increasing trend in later childhood and adolescence since 1973.

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  • 50% of deaths occurred within 2 hours of the final asthma attack; nearly half did not reach the hospital.
  • 10 cases died within a year of steroid cessation, with severe attacks often occurring during steroid reduction or after cessation.

    • Conclusions:

    • Asphyxia was the primary cause of death (23 cases).
    • Steroid withdrawal or reduction was associated with severe asthma attacks and mortality.
    • Emphasizes the need for adequate and vigorous initial therapy for severe pediatric asthma attacks.