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Frequent detection of TrkA expression in human neuroblastoma cell lines

Y Horii1, H Kuroda, T Sugimoto

  • 1Department of Pediatrics, Miyazaki Medical College, Japan. pedyoshi@post1.miyazaki-med.ac.jp

Acta Paediatrica Japonica : Overseas Edition
|January 20, 1999
PubMed
Abstract

No abstract available in PubMed .

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Enzyme-linked Receptors

Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...

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