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A three-year evaluation of hemostatic function in Singaporean Norplant acceptors
K Singh1, O A Viegas, S S Ratnam
1Department of Obstetrics and Gynaecology, National University Hospital, Singapore.
Abstract:
In a longitudinal study involving 100 Singaporean women, results indicate that the acceptors persist in having a possibly increased predisposition to thrombosis, as evidenced by a significant increase in platelet count and aggregability. Furthermore, the shortened prothrombin time and activated partial thromboplastin time, together with changes in vitamin K factors, still indicate the possible enhanced potential for hypercoagulation.