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Difference in urinary stone components between obese and non-obese patients
Yii-Her Chou1, Ching-Ming Su, Ching-Chia Li
1Department of Urology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University Hospital, No. 100 Tzyou 1st Road, Kaohsiung, 807, Taiwan. yihech@kmu.edu.tw
Urological Research
|December 17, 2010
Summary
Obesity is linked to higher rates of calcium oxalate and uric acid stones in urinary stone disease. Increased body mass index (BMI) correlates significantly with these stone types, particularly in overweight and obese individuals.
Area of Science:
- Urology
- Nephrology
- Metabolic Disorders
Background:
- Urinary stone disease prevalence is associated with body weight and Body Mass Index (BMI).
- Understanding the relationship between BMI and stone composition is crucial for prevention and treatment strategies.
Purpose of the Study:
- To investigate the differences in urinary stone composition across various BMI categories.
- To determine the association between BMI and specific types of kidney stones.
Main Methods:
- Infrared spectroscopy was used to analyze the composition of 907 urinary calculi collected between 2005 and 2008.
- Patients were categorized into normal weight (18.5≤ BMI <24), overweight (24≤ BMI <27), and obese (BMI ≥27) groups.
- Data on patient demographics, BMI, and stone composition were collected and analyzed.
Main Results:
- Obesity was prevalent in 38.8% of patients with urinary stone disease.
- The prevalence of calcium oxalate and uric acid stones increased significantly with higher BMI categories (P=0.002).
- A significant correlation was found between BMI and uric acid stones in overweight (OR=3.28) and obese (OR=4.35) groups.
Conclusions:
- Urinary stone disease incidence and prevalence are associated with BMI.
- Obese patients exhibit a higher percentage of uric acid and calcium oxalate stones compared to non-obese individuals.
- Calcium phosphate stone prevalence showed no significant difference between BMI groups.
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