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[Study of prognostic factors in patients with stage I non-small cell lung cancer]
Jun-zhong Ruan1, Yong Duan, Ming Qin
1Department of Thoracic Surgery, Beijing Chest Hospital, Beijing 101149, China.
Objective:
To analyze the prognostic factors for patients with stage I non-small cell lung cancer.
Methods:
A total of 224 patients with stage I non-small cell lung cancer operated from 1999 to 2004 were retrospectively reviewed. The clinical profiles of age, gender, T grade, type of resection, tumor pathological typing, tumor cell differentiation and post-operative chemotherapy were analyzed by SPSS 13.0 statistic software.
Results:
The five-year survival of stages Ia and Ib non-small cell lung cancer were 78.7% and 51.5% respectively. In univariate analysis, T grade and tumor cell differentiation were independent prognostic factors respectively. In multivariate analysis, T grade and tumor cell differentiation were independent prognostic factors for overall survival.
Conclusion:
There are significant differences in the five-year survival of stages Ia and Ib non-small lung cancer. Both tumor stage and tumor cell differentiation were independent prognostic factor for overall survival.
