Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Encephalitis ll: Pathophysiology

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...

Encephalitis l: Introduction

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Instrument Tracking Reduces Radiation Exposure and Increases Efficiency in Prone Lateral Lumbar Interbody Fusion: A Retrospective Cohort Study.

International journal of spine surgery·2026

Same author

Awake Spine Surgery: A 5-Year Institutional Experience in Academic and Ambulatory Settings.

Journal of neurosurgical anesthesiology·2026

Same author

Women in neurosurgical oncology: Mapping the milestones and shaping the future.

Neuro-oncology advances·2026

Same author

Leveraging biometric data for meaningful outcome assessments in the care of patients with brain tumors: a systematic review.

Journal of neuro-oncology·2026

Same author

A case of orbital solitary fibrous tumor with fast-growing budding morphology.

Orbit (Amsterdam, Netherlands)·2026

Same author

Radiographic and clinical predictors of surgical outcomes following endoscopic decompression for radiculopathy in adult degenerative scoliosis: A multi-center retrospective study.

Brain & spine·2026

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Atypical Rasmussen's encephalitis treated with temporal lobectomy.

Muhammad M Abd-El-Barr¹, Brenda Wu, Maryam Rahman

¹Department of Neurosurgery, University of Florida, Gainesville, Florida, USA.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia

|December 18, 2010

Summary

Rasmussen's encephalitis, a rare brain inflammation, can present in adults with new seizures. This case highlights a unique adult-onset presentation, expanding the known spectrum of this neurological condition.

More Related Videos

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Published on: August 16, 2024

Related Experiment Videos

Last Updated: Jun 5, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Published on: August 16, 2024

Area of Science:

Neurology
Neuroimmunology
Pediatric Neurology

Background:

Rasmussen's encephalitis is a rare, chronic inflammatory neurological disorder.
It typically affects children, causing progressive neurological decline and intractable seizures.
Surgical hemispherectomy is often required for seizure management.

Observation:

An adult woman presented with new-onset, medically refractory seizures.
Her seizures were not associated with progressive neurological deterioration.
She underwent a right anterior temporal lobectomy for seizure control.

Findings:

Pathological examination confirmed Rasmussen's encephalitis.
The patient achieved complete seizure freedom post-surgery.
She remained seizure-free for two years.

Implications:

This case demonstrates a unique adult-onset presentation of Rasmussen's encephalitis.
It suggests that Rasmussen's encephalitis may have a broader spectrum of clinical manifestations than previously recognized.
Further research is needed to understand the variability in presentation and long-term outcomes.