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Published on: October 20, 2017
Meningioangiomatosis: clinical-radiological features and surgical outcome
A Arcos1, R Serramito, J M Santín
1Departments of Neurosurgery, University of Santiago de Compostela, Spain. socrandrea@hotmail.com
Abstract:
Meningioangiomatosis (MA) is a rare, benign neoplastic disorder involving the cortex and leptomeninges, the sporadic form, commonly presents as refractory localization-related epilepsy, but could be asymptomatic especially in older patients. The imaging features may be entirely non-specific. Magnetic Resonance Imaging (MRI) erroneously suggests meningioma, lowgrade tumour or vascular malformations. The pathological findings are characterised by proliferation of meningothelial cells and leptomeningeal vessels and calcifications within the mass. Macroscopically there is dense thickening in the underlying cortex, often in a sharply defined area. In this article we report 3 cases of MA, neither of whom had a familiary history or stigmata of Neurofibromatosis (NF). We discuss and place particular emphasis on the clinical presentation and diagnosis imaging, as well as on the outcome. We also review the literature concerning about the aetiology, pathology findings and imaging features of MA.
Insights
Meningioangiomatosis (MA) is a rare brain disorder. This study highlights its varied presentation and diagnostic challenges, emphasizing the need for accurate imaging and pathological review.
Area of Science:
- Neurology
- Neurosurgery
- Pathology
Background:
- Meningioangiomatosis (MA) is a rare, benign neoplastic disorder affecting the brain's cortex and leptomeninges.
- Sporadic MA often presents as refractory epilepsy, but can be asymptomatic, particularly in older individuals.
Observation:
- Imaging findings, including MRI, can be non-specific and may mimic meningioma, low-grade tumors, or vascular malformations.
- Pathological hallmarks include proliferation of meningothelial cells, leptomeningeal vessels, and calcifications.
- Macroscopic examination reveals dense cortical thickening.
Findings:
- The article reports three cases of MA without familial history or Neurofibromatosis (NF) stigmata.
- Clinical presentation, diagnostic imaging, and outcomes are discussed.
- Literature review covers etiology, pathology, and imaging features of MA.
Implications:
- Accurate diagnosis of MA requires careful integration of clinical, imaging, and pathological data.
- Understanding MA's diverse presentation is crucial for appropriate patient management.
- Further research into MA's etiology and improved diagnostic criteria is warranted.
