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Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
Published on: October 24, 2018
Fulminant Neisseria meningitidis: role for extracorporeal membrane oxygenation
Michael S Firstenberg1, Daniele Blais, Erik Abel
1Division of Cardiothoracic Surgery, The Ohio State University Medical Center, Columbus, Ohio, USA. Michael.firstenberg@osumc.edu
Abstract:
Invasive meningococcal disease is often associated with complications of septic shock and central nervous system dysfunction. Extracorporeal membrane oxygenation is more commonly being used for respiratory failure and sepsis, but neurologic injury and potential coagulopathy are often considered relative contraindications. We report a successful case of complicated Neisseria meningitidis septic shock with disseminated intravascular coagulopathy requiring extracorporeal support.
Insights
Extracorporeal membrane oxygenation successfully treated severe meningococcal septic shock with disseminated intravascular coagulopathy. This case demonstrates ECMO
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Cardiopulmonary Support
Background:
- Invasive meningococcal disease frequently causes septic shock and neurological complications.
- Extracorporeal membrane oxygenation (ECMO) is increasingly used for sepsis and respiratory failure.
- Neurologic injury and coagulopathy are often considered contraindications for ECMO.
Observation:
- A patient presented with complicated Neisseria meningitidis septic shock.
- The patient developed disseminated intravascular coagulopathy (DIC).
- Extracorporeal support was deemed necessary.
Findings:
- Successful application of extracorporeal membrane oxygenation in a patient with meningococcal septic shock and DIC.
- ECMO provided vital cardiopulmonary support during critical illness.
- The patient's condition improved with extracorporeal support.
Implications:
- This case suggests that ECMO may be a viable option for select patients with severe meningococcal sepsis and coagulopathy.
- Careful patient selection and management are crucial when considering ECMO in this context.
- Further research is warranted to explore the role of ECMO in managing complex infectious disease complications.
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