[The effect of sinoaortic denervation by five selective methods on baroreflex sensitivity in conscious rats]

To measure the acute and chronic effects of left or/and right sinoaortic denervation (SAD), aortic denervation, and sinus denervation on baroreflex sensitivity (BRS) in conscious rats.

BRS was measured by means of a modified Smyth's method. The acute and chronic effects experiments were executed in 1st and 21st days after selective SAD respectively to compare the compensatory function.

(1) BRS decreased significantly after selective SAD. BRS of right SAD was significantly lower than that of left SAD, but they were able to compensate for each other. (2) The decrease in BRS of aortic denervation was more significant than that of sinus denervation, but the former had no significant compensatory function, which was different from the latter.

As for baroreflex, right sinoaortic nerves are more important than the left, but their ability to compensate for each other is comparable. Meanwhile, aortic nerves are more important than sinus nerves, and so is their compensatory function.