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Updated: Jun 5, 2026

The Resident-intruder Paradigm: A Standardized Test for Aggression, Violence and Social Stress
Published on: July 4, 2013
Neuropsychiatry of aggression
Scott D Lane1, Kimberly L Kjome, F Gerard Moeller
1Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1941 East Road Houston, TX 77054, USA.
Aggression poses significant risks in healthcare settings, stemming from various medical, neurologic, and psychiatric conditions. Individualized treatment plans combining medication and behavioral strategies are essential for managing aggressive patient behaviors.
Area of Science:
- Medical and psychiatric research
- Neuroscience
- Healthcare safety
Background:
- Aggression presents a significant challenge in healthcare, endangering patients and providers.
- Understanding the diverse origins of aggression is crucial for effective management.
Purpose of the Study:
- To highlight the medical problem of aggression in healthcare.
- To emphasize the need for comprehensive patient evaluation.
- To outline available treatment modalities for aggression.
Main Methods:
- Comprehensive patient evaluation to identify underlying causes of aggression.
- Review of pharmacologic and non-pharmacologic treatment options.
Main Results:
- Aggression can originate from medical, neurologic, or psychiatric disorders.
- Individualized treatment is necessary for each patient.
- Pharmacotherapy and non-pharmacologic interventions are key treatment components.
Conclusions:
- Aggression requires a thorough, individualized approach to evaluation and treatment.
- A combination of medical and behavioral interventions is often necessary.
- Ensuring patient and healthcare provider safety is paramount when managing aggression.
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