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Updated: Jun 5, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Photoaggravated hand and foot psoriasis
Rajani Nalluri1, Bavani Arun, Lesley E Rhodes
1Photobiology Unit, Dermatology Centre, University of Manchester, Manchester Academic Health Science Centre, Salford Royal Foundation Hospital, Manchester, UK.
Photodermatology, Photoimmunology & Photomedicine
|December 24, 2010
Summary
Most psoriasis patients improve with ultraviolet radiation, but some experience worsening. This case study highlights a rare instance of palmoplantar psoriasis evolving into photoaggravated psoriasis, emphasizing the need to consider photosensitivity in similar cases.
Area of Science:
- Dermatology
- Photobiology
Background:
- Psoriasis is a chronic inflammatory skin condition.
- Ultraviolet (UV) radiation often improves psoriasis symptoms.
- However, some individuals experience photosensitivity, leading to disease exacerbation.
Observation:
- A patient with long-standing palmoplantar psoriasis presented with an unusual change.
- The psoriasis distribution shifted from the palms to the dorsal aspect of the hands.
- This evolution suggested a new photosensitivity component.
Findings:
- The patient's condition was confirmed as photoaggravated psoriasis.
- Photoprovocation testing with solar-simulated radiation validated the photosensitivity.
- This documented a rare transformation of psoriasis presentation.
Implications:
- Clinicians should consider photosensitivity in psoriasis patients with changing lesion distribution.
- Hand and foot psoriasis may evolve into a photoaggravated form.
- Early recognition of photosensitivity is crucial for appropriate management.
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