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05:39
Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Anaplastic thyroid carcinoma initially presented with abdominal cutaneous mass and hyperthyroidism
Kyu-Hyoung Lim1, Keun-Wook Lee, Jee Hyun Kim
1Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
The Korean Journal of Internal Medicine
|December 24, 2010
Summary
This case report highlights a rare instance of anaplastic thyroid carcinoma (ATC) presenting with both an abdominal cutaneous metastasis and hyperthyroidism. These findings underscore the varied and potentially initial clinical manifestations of advanced ATC.
Area of Science:
- Oncology
- Endocrinology
- Dermatology
Background:
- Anaplastic thyroid carcinoma (ATC) is an aggressive endocrine malignancy.
- Cutaneous metastases from ATC are uncommon, and initial presentation with such findings is rare.
- Hyperthyroidism can be associated with thyroid malignancies, but its presentation alongside abdominal metastasis is noteworthy.
Observation:
- A 63-year-old female presented with a large, tender abdominal wall mass and a concurrent neck mass.
- Imaging revealed significant thyroid and periumbilical masses.
- Laboratory tests indicated a hyperthyroid state.
Findings:
- Pathological examination confirmed anaplastic thyroid carcinoma (ATC) of the thyroid.
- The abdominal mass was identified as a metastatic deposit of ATC.
- The patient's initial presentation included both abdominal cutaneous metastasis and hyperthyroidism.
Implications:
- This case is the first reported instance of ATC initially manifesting with both abdominal cutaneous metastasis and hyperthyroidism.
- It emphasizes the importance of considering advanced ATC in patients presenting with unusual metastatic patterns and endocrine disturbances.
- Early recognition of these varied presentations is crucial for timely diagnosis and management of ATC.
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