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Menstrual migraine: therapeutic approaches
1The City of London Migraine Clinic, London, UK; and Research Centre for Neuroscience within the Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK anne.macgregor@migraineclinic.org.uk.
Therapeutic Advances in Neurological Disorders
|December 25, 2010
Summary
Menstrual migraine is a common and debilitating condition. Acute treatments are effective, with perimenstrual prophylaxis and hormonal strategies offering further management options for this specific migraine type.
Area of Science:
- Neurology
- Gynecology
- Pharmacology
Background:
- Menstrual migraine is increasingly recognized as a prevalent and disabling condition.
- Specific diagnostic criteria now exist for menstrual migraine.
- There is a need for targeted treatment strategies.
Purpose of the Study:
- To review the current understanding and treatment of menstrual migraine.
- To evaluate the efficacy of existing therapeutic options.
- To explore future directions in managing menstrual migraine.
Main Methods:
- Literature review of diagnostic criteria and therapeutic trials for menstrual migraine.
- Analysis of published data on acute symptomatic treatments.
- Assessment of prophylactic and contraceptive management strategies.
Main Results:
- Diagnostic criteria have improved recognition of menstrual migraine.
- Acute migraine drugs are effective for symptomatic relief.
- Perimenstrual prophylaxis is a viable option when acute treatment is insufficient.
- Continuous contraceptive strategies may aid management, but data are limited.
Conclusions:
- Menstrual migraine is a significant condition requiring specific treatment.
- Current acute and prophylactic treatments show efficacy.
- Further research into hormonal therapies, including genomic and nongenomic actions of sex steroids, is warranted for future management.
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