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Updated: Jun 5, 2026

Using the Electroretinogram to Assess Function in the Rodent Retina and the Protective Effects of Remote Limb Ischemic Preconditioning
Published on: June 9, 2015
[The photopic electroretinogram in normal adult sd rat]
Hongling Chen1, Lifang Liu, Hongjie Lin
1Joint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong,Shantou 515041,China.
Purpose:
To study the characteristics of photopic flash electroretinogram (ERG) in normal adult SD rats.
Methods:
Sixty normal adult SD rats aged 9 to 12 weeks were enrolled in this study. Photopic flash ERG were recorded from these 60 SD rats. The results were statistically analyzed with SPSS software.
Results:
Stable a, b and PhNR wave could be recorded in each rat. Implicit time of a wave, implicit time and amplitude of PhNR fit normal distribution. Implicit time of PhNR was (124.6±8.5) ms with the smallest coefficient of variation of 0.07. The amplitude of PhNR was (11.3±4.2) μV and coefficient of variation was 0.37. There was no difference in the results between female and male rats.
Conclusion:
Photopic flash ERG is an objective method in evaluating the retinal function in SD rats and PhNR can be used as a sensitive index of inner retinal function.

