Central mucoepidermoid carcinoma of the mandible

Central mucoepidermoid carcinoma are extremely rare tumors, representing about 2 to 4% of all mucoepidermoid carcinomas. They are histologically low-grade cancers, usually affecting the mandible as uni- or multilocular radiographic lesions. Effective surgical treatment involving wide local excision or en bloc resection, allows patients to have a favorable prognosis after a long-term follow up. We report a case of central mucoepidermoid carcinoma affecting the mandible and discuss its clinical, radiographic, and histological findings, with a review of the literature.