Related Experiment Video
Updated: Jun 5, 2026

04:11
The Establishment of a Murine Maxillary Orthodontic Model
Published on: October 27, 2023
Endoscopic changes in the upper airway after mandibular distraction osteogenesis
Terrah Paul Olson1, J Scott McMurray, Delora L Mount
1Division of General Surgery, Department of Surgery, University of Wisconsin Hospital and Clinics, Madison, Wisconsin, USA.
The Journal of Craniofacial Surgery
|December 29, 2010
Summary
Mandibular distraction osteogenesis (MDO) improved airway obstruction in infants with micrognathia. While initial upper airway soft tissue changes were observed, complete symptom relief was achieved, highlighting MDO
Area of Science:
- Craniofacial surgery
- Pediatric airway management
- Medical imaging analysis
Background:
- Micrognathia in children often causes severe airway and feeding issues.
- Mandibular distraction osteogenesis (MDO) is a surgical treatment for significant micrognathia.
- Understanding upper airway (UA) soft tissue changes post-MDO is crucial for treatment efficacy.
Purpose of the Study:
- To evaluate changes in upper airway soft tissues after MDO using endoscopic imaging.
- To determine if these soft tissue changes correlate with symptom resolution in pediatric patients.
- To investigate the long-term stability of UA soft tissue modifications following MDO.
Main Methods:
- Retrospective review of 16 pediatric patients who underwent MDO between 2002 and 2007.
- Collection of demographic data, clinical symptoms, and endoscopic images (preoperative, early, and late postoperative).
- Quantitative analysis of UA soft tissue dimensions using ImageJ and statistical comparison of dimensional ratios.
Main Results:
- Significant changes in supraglottic space dimensions were noted in the early postoperative period after MDO.
- These dimensional changes in the supraglottic space were not sustained in the late postoperative period.
- All patients achieved complete resolution of airway obstruction despite the transient nature of some observed anatomical changes.
Conclusions:
- MDO leads to significant, albeit potentially temporary, increases in supraglottic space dimensions.
- Clinical improvement and resolution of airway obstruction occur consistently post-MDO, suggesting broader UA effects.
- Further research is needed to fully characterize UA soft tissue alterations and their relationship to clinical outcomes after MDO.

