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Infliximab for idiopathic deep cutaneous vasculitis refractory to cyclophosphamide
Marcelo Derbli Schafranski1, Giuliano Doretto Campanari
1Universidade Estadual de Ponta Grossa (UEPG), Rua Carlos Osternack, 111, 84040120, Ponta Grossa, Paraná, Brazil.
Abstract:
Cutaneous vasculitis can be classified as primary or idiopathic; or secondary, when it presents as a manifestation of connective tissue diseases, infections, drug reactions or malignancies. Although most of the idiopathic cases are self-limited and responsive to supportive measures and nonsteroidal anti-inflammatory drugs, potent immunosuppressants are sometimes required for the management of the refractory situations. Here we describe a case of a 32-year-old Caucasian female patient with history of idiopathic cutaneous deep vasculitis unresponsive to methotrexate, dapsone, and cyclophosphamide who was effectively treated with infliximab.
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