Search research articles

Related Concept Videos

Stem Cell Culture

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Intrapulpal thermal variation in standalone and dentifrice-assisted laser desensitisation at two time intervals.

BMC oral health·2026

Same author

Comparative evaluation of root dentin thickness following hand and rotary instrumentation of primary molar root canals using cone-beam computed tomography - an invitro study.

BMC oral health·2026

Same author

Comparative Efficacy of Four Different Types of Medicaments for Pulpotomy of Primary Molars: A Clinical and Radiographic Study.

International journal of clinical pediatric dentistry·2026

Same author

Evaluation of the Clinical Performance of Strip Crown Restorations with Composite Resin vs Glass Hybrid Restorative System for Primary Anterior Teeth of Children with Early Childhood Caries: A Double-blind Parallel Group Randomized Controlled Trial.

International journal of clinical pediatric dentistry·2025

Same author

Clinical and Radiographic Evaluation between Conventional Mineral Trioxide Aggregate and Gel-based Mineral Trioxide Aggregate in Indirect Pulp Therapy: A Randomized Clinical Trial.

International journal of clinical pediatric dentistry·2025

Same author

Evaluation of an interprofessional collaborative practice training module for the management of children with autism spectrum disorder.

Medical journal, Armed Forces India·2024

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Published on: November 24, 2012

Dental pulp stem cells from primary and permanent teeth: quality analysis.

Shobha Tandon¹, Rooposhi Saha, Ramesh Rajendran

¹Manipal College of Dental Sciences, Manipal, Karnataka, India. drtandons@yahoo.com

The Journal of Clinical Pediatric Dentistry

|December 31, 2010

Summary

This summary is machine-generated.

Inflamed dental pulp from children aged 5-14 is a viable source for adult stem cells. Healthy pulp tissue was insufficient for stem cell harvesting, unlike inflamed samples.

More Related Videos

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

Primary Culture of Dental Pulp Stem Cells

Primary Culture of Dental Pulp Stem Cells

Published on: May 5, 2023

Related Experiment Videos

Last Updated: Jun 5, 2026

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Published on: November 24, 2012

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth

Published on: May 17, 2024

Primary Culture of Dental Pulp Stem Cells

Primary Culture of Dental Pulp Stem Cells

Published on: May 5, 2023

Area of Science:

Dental Pulp Stem Cells
Regenerative Medicine
Tissue Engineering

Background:

Dental pulp contains mesenchymal stem cells with multipotent differentiation capabilities.
Identifying reliable sources of adult stem cells is crucial for regenerative medicine applications.

Purpose of the Study:

To isolate and characterize stem cells from healthy and inflamed dental pulp in children.
To assess the differentiation potential of these dental pulp stem cells into multiple lineages.

Main Methods:

Dental pulp tissues were obtained from children aged 5-14 undergoing pulp therapy or orthodontic extractions.
Cell culture, isolation, and differentiation techniques were employed.
Expression of cell surface markers was analyzed and compared to bone marrow stem cells.

Main Results:

No significant difference in surface marker expression was observed between inflamed dental pulp and bone marrow.
Healthy primary dental pulp was insufficient for stem cell harvesting.
Healthy permanent dental pulp also failed to yield sufficient stem cells.

Conclusions:

Inflamed dental pulp discarded during pulp therapy represents a promising source for adult stem cells.
These stem cells possess characteristics comparable to bone marrow stem cells.