[Anesthesia with dormicum-aneksat in obstetrical-gynecological operations]

Area of Science:

• Anesthesiology and Pharmacology

Background:

• Dormicum (midazolam) is a sedative used in anesthesia.
• Anexat (flumazenil) is a benzodiazepine antagonist.

Purpose of the Study:

• To evaluate the efficacy and safety of Dormicum-Anexat anesthesia in gynecological procedures.
• To assess the impact of Anexat on patient recovery, including waking, awareness, and orientation.

Main Methods:

• Administered Dormicum-Anexat anesthesia to 38 women undergoing abdominal gynecological operations.
• Studied a separate group of 32 women undergoing induced pregnancy interruption.
• Monitored clinical parameters: respiration, arterial blood pressure, and acid-base balance.
• Evaluated the reversal effect of Anexat on Dormicum's sedation.

Main Results:

• Dormicum-Anexat anesthesia was successfully administered in both patient groups.
• Anexat effectively neutralized the sedative effects of Dormicum in all patients.
• Clinical parameters remained stable during anesthesia.
• Patient recovery, including waking, awareness, and orientation, was positively influenced by Anexat.

Conclusions:

• Dormicum-Anexat provides a safe and effective anesthetic combination for gynecological surgery and pregnancy interruption.
• Anexat is a reliable antagonist for Dormicum, ensuring prompt and complete patient recovery.