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Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
Published on: October 16, 2013
Idiopathic scoliosis
Per Trobisch1, Olaf Suess, Frank Schwab
1Shriners Hospital for Children, 3551 N Broad Street, Philadelphia, PA 19140, USA. pertrobisch@gmail.com
Deutsches Arzteblatt International
|December 31, 2010
Summary
Scoliosis, a spinal deviation, affects 1-2% of adolescents and over 50% of those over 60. Early diagnosis and age-appropriate treatment, including bracing or surgery for children and potentially surgery for adults with sagittal imbalance, are crucial.
Area of Science:
- Orthopedics
- Radiology
- Pediatrics
Background:
- Scoliosis is defined as a spinal deviation exceeding 10° on X-ray.
- Idiopathic scoliosis lacks an identifiable underlying cause.
- It presents as a three-dimensional spinal axis deviation.
Purpose of the Study:
- To review current understanding and treatment guidelines for scoliosis.
- To highlight the importance of early diagnosis in scoliosis management.
Main Methods:
- A selective literature review was conducted.
- Recommendations from German and international medical societies were considered.
Main Results:
- Scoliosis prevalence is 1-2% in adolescents and over 50% in individuals over 60.
- Treatment goals focus on preventing progression in children.
- Children with >20° curves need bracing; >45° require surgery.
- Adult treatment is individualized, with surgery considered for those with sagittal imbalance.
Conclusions:
- Scoliosis is a prevalent condition.
- Timely diagnosis significantly impacts treatment selection and outcomes.
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