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Removal of immunosuppressive substance in cancer patients' serum
O Ishiko1, M Deguchi, I Tatsuta
1Department of Obstetrics and Gynecology, Osaka City University Medical School.
Japanese Journal of Cancer Research : Gann
|June 1, 1990
Abstract:
Anemia-inducing substance (AIS) appears in plasma as cancer progresses. In this study, a non-coated charcoal column was used to remove AIS from the cachectic plasma obtained from patients with advanced cancer. AIS could be completely removed by 6 cycles of adsorption using this column. Similar data were obtained in an experiment using VX-2-transplanted rabbits. These observations raised the possibility that plasmapheresis with a non-coated charcoal column may be available as a new means of immunotherapy for advanced cancer.